Berlin Beat of Running Study - Frequency of Cardiac Arrhythmias & Cerebral Lesions in Marathon Runners
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 110
- 试验地点
- 1
- 主要终点
- Rate of cardiac arrhythmias in marathon runners detected by mobile ECG-recording
研究概览
简要总结
This prospective observational study will investigate the frequency of new onset atrial fibrillation (AF) and of further cardiac arrhythmias as well as of (clinically silent) cerebral lesions in endurance runners before, during and after the BMW-Berlin Marathon 2011.
详细描述
Up to 120 experienced marathon runners will participate in the "Berlin Beat of Running Study" and will wear a transportable electrocardiogram (ECG) recorder at least 24 hours before, during and 24 hours after the BMW-Berlin Marathon. All participants will undergo brain MRI examinations to detect cerebral lesions within days before and after the marathon race, respectively. Moreover, serial blood samples will be taken a few days before, immediately after as well as a few days after the BMW-Berlin Marathon.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 35 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 35-65 years
- •at least 2 marathon runs within the last 5 years
- •weekly running of at least 40 km
排除标准
- •Known cardiac arrhythmia or prior stroke
- •contraindication for MRI.
结局指标
主要结局
Rate of cardiac arrhythmias in marathon runners detected by mobile ECG-recording
时间窗: Up to 48 hours after the marathon race.
During ECG recording
次要结局
- Rate of (clinically silent) cerebral lesions detected by 3 Tesla brain MRI.(3 days)
研究者
Karl Georg Haeusler
MD
Charite University, Berlin, Germany