Berlin Beat of Running Study

Completed

• Conditions: Cardiac Arrhythmia; Stroke; Brain Lesion

• Registration Number: NCT01428778
• Lead Sponsor: Charite University, Berlin, Germany

Brief Summary

This prospective observational study will investigate the frequency of new onset atrial fibrillation (AF) and of further cardiac arrhythmias as well as of (clinically silent) cerebral lesions in endurance runners before, during and after the BMW-Berlin Marathon 2011.

Detailed Description

Up to 120 experienced marathon runners will participate in the "Berlin Beat of Running Study" and will wear a transportable electrocardiogram (ECG) recorder at least 24 hours before, during and 24 hours after the BMW-Berlin Marathon. All participants will undergo brain MRI examinations to detect cerebral lesions within days before and after the marathon race, respectively. Moreover, serial blood samples will be taken a few days before, immediately after as well as a few days after the BMW-Berlin Marathon.

Study Timeline

• Study First Submitted: 2011-08-31
• Study Start: 2011-09
• Study First Submitted QC: 2011-09-02
• Study First Posted: 2011-09-05
• Primary Completion: 2012-09
• Study Completion: 2012-09
• Status Verified: 2016-11
• Last Update Submitted: 2016-11-07
• Last Update Posted: 2016-11-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

• Age 35-65 years
• at least 2 marathon runs within the last 5 years
• weekly running of at least 40 km

Exclusion Criteria

• Known cardiac arrhythmia or prior stroke
• contraindication for MRI.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Rate of cardiac arrhythmias in marathon runners detected by mobile ECG-recording	Up to 48 hours after the marathon race.	During ECG recording

Secondary Outcome Measures

Name	Time	Method
Rate of (clinically silent) cerebral lesions detected by 3 Tesla brain MRI.	3 days	Up to 3 days after marathon.

Trial Locations

Locations (1)

Center for Stroke Research Berlin; 🇩🇪 Berlin, Germany