Early Surgical Effects and Influencing Factors of High Tibial Osteotomy in the Treatment of Knee Osteoarthritis

Completed

• Conditions: Osteoarthritis, Knee
• Interventions: Procedure: High tibial osteotomy

• Registration Number: NCT06512948
• Lead Sponsor: Shufeng Li

Brief Summary

Exploring the factors influencing postoperative functional recovery after high tibial osteotomy

Detailed Description

A retrospective study was conducted on patients who underwent HTO at the First Affiliated Hospital of Shandong First Medical University from January 2018 to December 2020, and the preoperative and postoperative imaging indicators \[medial proximal tibial angle (MPTA), joint line intersection angle (JLCA), hip-knee-ankle angle (HKA angle), knee weight-bearing line percentage (WBL%), postoperative distraction distance, postoperative distraction angle\] and knee joint function score \[including the American Hospital for Special Surgery (HSS) knee score, American Knee Society score (KSS), Lysholm score, Western Ontario and McMaster Universities Osteoarthritis Index score (WOMAC), and all were included in logistic regression analysis to study the surgical effect and impact of HTO factor

Study Timeline

• Study Start: 2021-01-01
• Primary Completion: 2021-12-01
• Study Completion: 2021-12-01
• Study First Submitted: 2024-01-04
• Status Verified: 2024-07
• Study First Submitted QC: 2024-07-16
• Last Update Submitted: 2024-07-16
• Study First Posted: 2024-07-22
• Last Update Posted: 2024-07-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 78

Inclusion Criteria

• Medial knee OA, varus deformity is mainly in the tibia
• Aged ≤70 years old, with higher requirements for future activities
• Knee joint extension is limited to ≤10°, and flexion is >90°
• Body Mass Index (BMI) ≤ 40
• No subchondral bone wear

Exclusion Criteria

• There is a history of fracture or surgery of the lower limb on the operated side
• Traumatic KOA
• Combined with nerve, muscle or connective tissue diseases
• Incomplete imaging data and loss of follow-up

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Logistics regression model	High tibial osteotomy	This article is a retrospective study, which mainly incorporates patients' preoperative and postoperative imaging parameters and demographic data into Logistics regression analysis to analyze factors that may affect the surgical effect. No interventions such as medication are involved.

Primary Outcome Measures

Name	Time	Method
Imaging parameters	an average of 1 year after the surgery	opening angle

Secondary Outcome Measures

Name	Time	Method
function score	an average of 1 year after the surgery	Western Ontario and McMaster Universities Osteoarthritis Index

Trial Locations

Locations (1)

The First Affiliated Hospital of Shandong First Medical University; 🇨🇳 Jinan, Shandong, China