Rotational thromboelastometry versus standard coagulation tests for adult liver transplant recipients with thrombophilia
Not Applicable
Completed
- Conditions
- Digestive SystemLiver cirrhosis
- Registration Number
- PACTR201712002847839
- Lead Sponsor
- Department of Anaesthesiology, Faculty of Medicine, University of Alexandria
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Adult patients with end stage liver disease scheduled for live donor liver transplantation
Exclusion Criteria
- Active overt infection
- Patients undergoing re-transplantation.
- Recipients receiving grafts with multiple vessel anomilies (trifurcated portal vein, double hepatic artery)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
How does rotational thromboelastometry (ROTEM) assess coagulation dynamics in thrombophilic liver transplant recipients compared to standard tests?
What are the key molecular mechanisms of coagulopathy in liver cirrhosis patients with thrombophilia undergoing transplantation?
Which biomarkers correlate with ROTEM-guided anticoagulant management outcomes in adult liver transplant recipients with Factor V Leiden or Prothrombin G20210A mutations?
What adverse events are associated with ROTEM-based coagulation monitoring versus conventional tests in liver transplant patients with inherited thrombophilia?
How does ROTEM-guided hemostatic therapy compare to standard coagulation testing in reducing post-transplant thromboembolic complications in cirrhotic patients with hypercoagulable states?