Healthy Diet for Healthy Moms and Babies
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 34
- 试验地点
- 1
- 主要终点
- Gestational weight gain
研究概览
简要总结
The purpose of this clinical study is to collect baseline information on dietary habits and metabolic risk factors, and to examine the effects of a dietary intervention focusing on fiber and antioxidant rich berries on the development of gestational diabetes, maternal glucose and lipid control and inflammation in obese pregnant women at risk of developing diabetes. With the ongoing epidemic of obesity, the prevalence of gestational diabetes is significantly increasing and the goal of this research is to identify optimal dietary strategies that can reverse this condition or control the rise in blood glucose among those with already developed diabetes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Care Provider)
入排标准
- 年龄范围
- 19 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •BMI > or = 30, <20 weeks gestation and singleton pregnancy with the following options: previous history of gestational diabetes and/or family history of diabetes
排除标准
- •• Twin or multiple pregnancy
- •Chronic pre-pregnancy conditions (CHD, cancer, diabetes)
- •Gastrointestinal conditions
- •Allergic to berries and fiber
- •Vegetarian food habits or special diets
- •Not proficient in English and/or unable to provide consent
研究组 & 干预措施
Prenatal Care/Nutrition Education
Participants were given nutrition educational counseling on healthy dietary habits and gestational weight gain as part of standard prenatal care.
Dietary Intervention
Participants were given dietary blueberries (2 cups) and soluble fiber (12g). They also received nutrition educational counseling on healthy dietary habits and gestational weight gain as part of standard prenatal care.
干预措施: Blueberry + soluble fiber (Dietary Supplement)
结局指标
主要结局
Gestational weight gain
时间窗: 20 weeks
Maternal weight gain in lbs
Maternal inflammation
时间窗: 20 weeks
C-reactive protein as a stable biomarker of inflammation
Gestational glycemia
时间窗: 20 weeks
Maternal blood glucose and HbA1c as measures of glycemia
Maternal serum lipids
时间窗: 20 weeks
Conventional total, LDL-cholesterol and their particle size to describe lipid profiles
次要结局
- Maternal dietary intakes(20 weeks)
- Maternal biomarkers of atherosclerosis(20 weeks)
研究者
Arpita Basu
Associate Professor
University of Nevada, Las Vegas