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Manual Therapy on the Improvement of Functional Disability in Patients With Chronic Non Specific Low Back Pain

Not Applicable
Completed
Conditions
Back Pain Lower Back Chronic
Interventions
Procedure: Manual therapy and active exercises
Procedure: Detuned ultrasound and active exercises
Registration Number
NCT01496144
Lead Sponsor
University of Applied Sciences of Western Switzerland
Brief Summary

Background: Models have tried to explain the driving mechanisms behind chronic non specific low back pain (CNSLBP) in order to propose better appropriate conservative treatment. Altered responses at spinal and/or supraspinal level may affect the perception of pain and degree of disability of CNSLBP patients. Recent clinical recommendations still propose active exercises (AE) for CNSLBP. However, acceptance of exercises by patients may be limited by pain-related manifestations. Current evidences suggest manual therapy (MT) induces a short-term analgesic effect through neurophysiological mechanisms at peripheral, spinal and cortical levels. The aim of this study was first, to assess whether MT has an instant analgesic effect, and second, to compare the long-lasting effect on functional disability of MT followed by AE to sham therapy (ST) followed by AE. Methods: Forty-two CNSLBP patients without co-morbidities, randomly distributed into 2 treatment groups, received either spinal manipulation/mobilization (first intervention) plus AE (MT group; n = 22), or detuned ultrasound (first intervention) plus AE (ST group; n = 20). Eight therapeutic sessions were delivered over 4 to 8 weeks. Instant analgesic effect was obtained by measuring pain intensity (Visual Analogue Scale) before and immediately after the first intervention of each therapeutic session. Pain intensity, disability (Oswestry Disability Index) and fear-avoidance beliefs (Fear-Avoidance Beliefs Questionnaire) were determined before treatment, after the 8th therapeutic session, and at 3- and 6-month follow-ups.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
42
Inclusion Criteria
  • suffering from non specific low back pain with or without symptoms in the lower extremity for a period between 12 and 26 weeks
  • can maintain the usual medication
Exclusion Criteria
  • spinal fracture or surgery within the previous 6 months
  • pregnancy
  • neoplasia
  • spinal infection
  • spinal inflammatory arthritis
  • low back pain of visceral origin
  • severe sensitive and/or motor radicular deficit from nerve root origin of less than 6 months
  • score of 3/5 or more on the Waddell Score
  • on sick leaves from work for 6 months or more
  • psychiatric disorders
  • opioid medication
  • patient unable to collaborate (linguistic barrier; cognitive impairments)
  • radiologic abnormalities other than degenerative disease
  • clinical neurogenic claudication.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Manual therapy and active exercisesManual therapy and active exercisesSpinal manipulation /mobilisation
Detuned ultrasound and active exercisesDetuned ultrasound and active exercises-
Primary Outcome Measures
NameTimeMethod
Visual Analogue Scale - VAS-painDuring treatment, over a period of 4 to 8 weeks

self-report of clinical pain intensity, consisting of a 10 cm horizontal line scale on which is added the statements "no pain" on the left and "maximum intensity of pain" on the right

Secondary Outcome Measures
NameTimeMethod
Fear-avoidance beliefs (Fear-Avoidance Beliefs Questionnaire - FABQ)Before randomization and untill 6 months after the end of treatment

measures level of fear and avoidance beliefs about work and physical activity in patients with low back pain

Trial Locations

Locations (1)

Département de l'appareil locomoteur (DAL), Centre Hospitalier Universitaire Vaudois (CHUV)

🇨🇭

Lausanne, Vaud, Switzerland

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