Effect of Phototherapy Applied During Combined Training on Performance and Post-exercise Recovery: Study Protocol of a Randomized Controlled Trial by Stratified Sample, Double-blind, Placebo-controlled
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 45
- 主要终点
- Change from 6-week Maximal voluntary isometric contraction at 12-week of training
研究概览
简要总结
Introduction: Recent studies have shown positive results from the application of phototherapy for the improvement of performance and acceleration of the recovery process both in the application before and after exercise. However, the effects of phototherapy during combined training and after a primary adaptation process remain unclear.
Research objectives: The primary objective of the study is to analyze and compare the effects of phototherapy using different light sources (laser and light emmiting diode - LED) interacting with combined training on clinical, functional, and psychological outcomes and vascular endothelial growth factor. The secondary objective is to compare the benefits provided by phototherapy in participants with different levels of training adaptation.
Design: A controlled trial, double-blind, placebo-controlled will be conducted with stratified randomization and concealed allocation.
Participants and Setting: After fulfilling the eligibility criteria, forty-five male participants will participate in the study.
Procedure: In phase 1, the participants will perform six-weeks of combined training (sprints and squats). In phase 2, participants will be allocated, through stratified randomization (based on adaptation capacity to training), into three groups: active phototherapy group (AG), placebo phototherapy group (PG), and control group (CG). A new six-week training period will then start. In this phase the participants will carry out training normally with the adjusted loads and between sprints and squats will receive the recovery strategy related to the group to which they belong.
Intervention: Active and placebo phototherapy will be applied by a trained therapist, between sprints and squats. During the period of recovery strategies for the AG and PG, the CG participants will remain seated for passive recovery, supervised by an independent therapist.
Measurements: The measurements include clinical, functional, and psychological outcomes and vascular endothelial growth factor.
详细描述
Introduction: Recent studies have shown positive results from the application of phototherapy for the improvement of performance and acceleration of the recovery process both in the application before and after exercise. However, the effects of phototherapy during combined training and after a primary adaptation process remain unclear.
Research objectives: The primary objective of the study is to analyze and compare the effects of phototherapy using different light sources (laser and LEDs) interacting with combined training on clinical, functional, and psychological outcomes and vascular endothelial growth factor. The secondary objective is to compare the benefits provided by phototherapy in participants with different levels of training adaptation.
Design: A controlled trial, double-blind, placebo-controlled will be conducted with stratified randomization and concealed allocation.
Participants and Setting: After fulfilling the eligibility criteria, forty-five male participants will participate in the study. The inclusion criteria include: healthy male, aged between 18-30 years who agree to participate in the study. Participants with the following will be excluded from the study: presence of anemia, inflammation, diabetes, history of metastasis or muscle injury in the lower limbs or spine in the previous six months, and occurrence of musculoskeletal injury during the study.
Procedure: In phase 1, the participants will perform six-weeks of combined training (sprints and squats). In phase 2, participants will be allocated, through stratified randomization (based on adaptation capacity to training), into three groups: active phototherapy group (AG), placebo phototherapy group (PG), and control group (CG). A new six-week training period will then start. In this phase the participants will carry out training normally with the adjusted loads and between sprints and squats will receive the recovery strategy related to the group to which they belong.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Healthy (self-report);
- •Male gender;
- •Aged between 18-30 years;
- •Agreement to participate through signed statement of informed consent
排除标准
- •Presence of anemia, inflammation, or diabetes;
- •History of metastasis.
- •History of muscle injury in the lower limbs or spine in the previous six months;
- •Occurrence of musculoskeletal injury during the study.
结局指标
主要结局
Change from 6-week Maximal voluntary isometric contraction at 12-week of training
时间窗: Change between 6-week and 12-week of training
Prior to the MVIC evaluation, participants will conduct a warm up consisting of 10 repetitions of knee flexion-extension at 180°.s-1 throughout the range of motion. The MIVC will be determined by the highest maximal isometric torque over three contractions of five seconds at 60° of knee flexion (with 0° corresponding to the maximum extension). The repetitions will be separated by a 2-minute rest interval. Participants will be instructed to perform maximal contractions and verbally encouraged by the researcher during the evaluation.
次要结局
- Pain threshold(Baseline, 5-week, after 6-week, 12-week, after 13-week of training)
- Perception of recovery(5-week, 12-week of training)
- Vascular endothelial growth factor(Baseline, after 6-week, after 13-week)
- Strength and power test(Baseline, after 6-week, after 13-week of training)
- Maximum oxygen consumption (VO2max)(Baseline, after 6-week, after 13-week of training)
- Muscle soreness(Baseline, 5-week, after 6-week, 12-week, after 13-week of training)
- Psychological questionnaire(Baseline, before 5-week, before 12-week of training)
- Belief questionnaire(After 6-week, after 13-week of training)
- Squat jump(Baseline, after 6-week, after 13-week of training)
- Sprint test(Baseline, after 6-week, after 13-week of training)
- Perception of exertion(5-week, 12-week of training)