Evaluation of sleep, quality of life and ability to perform exercise before and after the use of an apparatus to treat sleep disorders in adults with non-fibrocystic bronchiectasis and obstructive sleep apnea
Not Applicable
- Conditions
- BronchiectasisC08.618.085.852.850SleepObstructive Sleep ApneaPolysomnography.C08.127.384F02.830.855E01.370.520.625
- Registration Number
- RBR-4q83kx
- Lead Sponsor
- Centro Universitário Augusto da Motta
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Patients with clinical diagnosis of BNF (after confirmation by HRCT and sweat test) of both genders; between 18 and 90 years old; after agreeing to participate in the study; signing the ICF; with no cognitive deficit that would interfere in the comprehension to answer the questionnaires; clinical stability at least 1 month; long-term bronchodilator use; presence of OSA confirmed by PSG.
Exclusion Criteria
Patients with bronchiectasis due to CF (chloride level in sweat> 60 mmol / L); smoking history; presence of other pulmonary diseases (eg COPD and asthma) and / or other comorbidities that could influence the diagnosis and/or prognosis in the outcome of the disease.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction in mean apnea and hypopnea index determined by PSG and increase in walking meters at 6MWT and faster to achieve TGlittre after 3 months of PAP use in adults with BNF and OSA.
- Secondary Outcome Measures
Name Time Method Pulmonary function was complete with improvement in FEV1 and FVC, reduced levels of inflammatory biomarkers collected in the blood, improved quality of life questionnaires and a faster rate of ADLs after 3 months of PAP use in adults with BNF and AOS.