Changes in body fluid parameters measured by bioimpedance spectroscopy in response to different types of fluid infused in healthy volunteers

Not Applicable

Completed

• Conditions: Not Applicable

• Registration Number: KCT0001791
• Lead Sponsor: Asan Medical Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 11 March 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

body mass index 18.5-25 kg per square meter
-volunteers who consented to participate in the trial

Exclusion Criteria

-previously diagnosed hepatic, renal, gastrointestinal, respiratory, musculoskeletal, endocrine, neuropsychotic, hematooncologic, cardiovascular disease or clinically equivalent disease
-hemoglobin < 10 g/dl
-estimated glomerular filtration rate < 60 ml/min
-participated in clinical trial of other drugs within 60 days before screening
-donated blood more than 450 ml within 60 days before screening
-hepatitis B or C carrier, previously diagnosed syphilis, acquired immunodeficiency disease
-hyperhidrosis
-experience of acute disease which can cause dehydration (ex,. diarrhea, acute gastroenteritis) within 3 days before fluid administration
-Alcohol intake within 3 days before fluid administration
-Patients who are considered by the investigator to be unsuitable to participate in the study for any other reason not mentioned in the inclusion and exclusion criteria.

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change of intracellular, extracellular, and their ratio compared to baseline value in bioimpedance spectroscopy

Secondary Outcome Measures

Name	Time	Method
Plasma and blood volume measured by indocyanin green dilution technique;Adverse events