Measurement of Body Fat in Infants
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Whole Body Fat Mass
研究概览
简要总结
Up to 10 infants will complete the study aimed to establish a technique for measuring whole body adiposity and brown adipose tissue in infant subjects using dual energy x-ray absorptiometry and magnetic resonance imaging, respectively.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 14 Days 至 28 Days（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy, full-term infant
- •aged 14-28 days at Visit 1
排除标准
- •born preterm (<37 weeks gestation)
- •implanted metal or electronic objects that render MRI unsafe
- •unable to complete 2 clinic visits 1-10 days apart at Pennington Biomedical Research Center
结局指标
主要结局
Whole Body Fat Mass
时间窗: 1 day
Whole body fat mass will be measured in infant subjects using dual energy x-ray absorptiometry.
Average Brown Adipose Tissue Volume at Second Visit
时间窗: 1 day
Magnetic resonance imaging were traced for lipid: water ratio in the supraclavicular region. Brown adipose tissue volume was calculated by summing all brown adipose tissue volume in the supraclavicular region with a lipid: water ration (or fat signal fraction) between 10-50%.
Average Brown Adipose Tissue Volume at First Visit
时间窗: 1 day
Magnetic resonance imaging were traced for lipid: water ratio in the supraclavicular region. Brown adipose tissue volume was calculated by summing all brown adipose tissue volume in the supraclavicular region with a lipid: water ration (or fat signal fraction) between 10-50%.
次要结局
- Average Fat Signal Fraction of Brown Adipose Tissue at First Visit(1 day)
- Average Fat Signal Fraction of Brown Adipose Tissue at Second Visit(1 day)
- Reliability of Average Brown Adipose Tissue Volume Measurement Between the First and Second Visit(2 days within 10 days apart)
研究者
Leanne Redman
Assistant Professor
Pennington Biomedical Research Center