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SPP100 (Aliskiren) Regimen in Patients With Severe Hypertension

Phase 3
Completed
Conditions
Hypertension
Registration Number
NCT00299806
Lead Sponsor
Novartis
Brief Summary

Assessing the safety and efficacy of SPP100 (Aliskiren) regimen in patients with severe hypertension

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
39
Inclusion Criteria
  • Age: 20 - 80 years old
  • Gender: Male or female
  • Status: Outpatients
  • severe hypertension
Exclusion Criteria
  • Patients with a clinically significant allergy
  • Patients who have received other investigational drug
  • Alcoholic patients

Other protocol-defined inclusion/exclusion criteria may apply

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Incidence of adverse events after 8 weeks
Secondary Outcome Measures
NameTimeMethod
Change from baseline in mean sitting systolic and diastolic blood pressure after 8 weeks
Average sitting diastolic blood pressure < 90 mmHg or a reduction from baseline of > 10 mmHg after 8 weeks.
Average sitting systolic blood pressure/mean sitting diastolic blood is < 160/100 mmHg or blood pressure reduction from baseline is > 20/10 mmHg after 8 weeks

Trial Locations

Locations (1)

Novartis Pharmaceuticals

🇯🇵

Japan, Japan

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