Screening of genes using advanced sequencing method in patients with heart problem by birth, to find the link between affected genes and the disease
Not Applicable
- Conditions
- Health Condition 1: Q209- Congenital malformation of cardiacchambers and connections, unspecified
- Registration Number
- CTRI/2023/10/059320
- Lead Sponsor
- Department of Science and Technology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
The study subjects will be pediatric live births and adult patients. The patients will be thoroughly screened for breathing problems, failure to thrive, heart murmur, fatigue, and family history by the cardiologist. Phenotypic data for the affected individuals and their family members will be obtained from the detailed clinical evaluation based on Electrocardiogram, Two-dimensional Echocardiography, cardiac catheterization and surgical findings. Peripheral blood samples from all the participants will be collected in EDTA K2 tubes after informed consent as per the extensive clinical criteria.
Exclusion Criteria
Patients with syndromic congenital heart defects will be excluded from the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method