Study of the Efficacy and Safety of Five Percent Benzoyl Peroxide Versus Fusidic Acid in the Treatment of Pitted Keratolysis A Randomised Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 84
- 试验地点
- 1
- 主要终点
- 1. Measurement of efficacy of modalities on the basis of visual analogue scale.
研究概览
简要总结
Pitted keratolysis is a common infective skin disease caused by gram-positive bacteria affecting the soles of feet. Fusidic Acid is one antibiotic that is a frequently applied topically to treat infections of the skin and soft tissues. It is one of the mainstay treatments in Pitted Keratolysis. Benzoyl peroxide having antimicrobial as well as keratolytic properties is being used for the treatment for acne vulgaris and is one of the newer treatment modalities for Pitted Keratolysis. This Study is undertaken to Determine the Efficacy and Safety of 5% Benzoyl Peroxide Versus Fusidic Acid in the Treatment of Pitted Keratolysis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Newly diagnosed pitted keratolysis.
排除标准
- •1.Patients on antiperspirants ( such as aluminium chloride, aluminium zirconium and aluminium chlorohydrate) 2.Patients with hypersensitivity to drugs (topical fusidic acid and benzoyl peroxide) 3.Patients on topical sulfone products (e.g., dapsone) 4.Patients on topical hydroquinone.
结局指标
主要结局
1. Measurement of efficacy of modalities on the basis of visual analogue scale.
时间窗: Treatment for a period of 4 weeks and patient is then followed up at week 2 and week 4 after treatment commencement
2.Measurement of safety of modalities on the basis of visual discomfort scale.
时间窗: Treatment for a period of 4 weeks and patient is then followed up at week 2 and week 4 after treatment commencement
次要结局
- Adverse effects post treatment with 5% benzoyl peroxide and fusidic acid in treatment of pitted keratolysis(every 2 weeks follow up for a treatment period of 4 weeks)
研究者
Dr Namrata Sandeep Kenkre
Sri Devaraj Urs Medical College