Virtual Autopsy in Cardiology, Cardio- and Vascular-Surgery
- Conditions
- Death
- Registration Number
- NCT02502955
- Lead Sponsor
- Universitätsklinikum Hamburg-Eppendorf
- Brief Summary
Today complex vascular and cardiological interventions are performed in severely ill patients.
Autopsy is the reference standard for quality control for almost two centuries, but autopsy rates for patients dying in hospitals are decreasing rapidly.
Virtual autopsy has shown to be a good alternative for classic autopsy.
- Detailed Description
Patients dying within 96h after a cardiological intervention of a cardio-/vascular-surgery are eligible to be included in the study.
If the next of kin give oral informed consent a virtual autopsy based on a CT angiography followed by a classic medical autopsy will be performed.
Ante mortem findings will be compared to findings from both autopsy methods and presented to the clinicians.
Primary outcome will be the inter-method agreement. Secondary outcome will be the satisfaction of the clinicians evaluated by a standardized questionnaire.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 50
- 18 years or older AND
- dying after a cardiological intervention or a cardio-/vascular surgery AND
- oral informed consent from next of kind
- not fulfilling all inclusion criteria
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Agreement of virtual autopsy and medical autopsy (inter-method agreement) 1 week Diagnoses made by virtual autopsy will be compared to diagnoses made by classic autopsy.
- Secondary Outcome Measures
Name Time Method Quality evaluation (satisfaction of the clinicians evaluated by a standardized questionnaire) 2 weeks Diagnoses made by any autopsy method will be compared to ante mortem diagnoses.
Trial Locations
- Locations (1)
Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf (UKE)
🇩🇪Hamburg, Germany