*Tackle your Tics: effectiveness of a brief, intensive group-based exposure therapy programme for children with tic disorders: a randomized controlled trial*

Completed

• Conditions: tic disorder / Tourette Syndrome; 10037173

• Registration Number: NL-OMON49057
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 104

Inclusion Criteria

(a) youths aged 9 to 17 years, (b) diagnosed with Tourette
Syndrome or persistent (motor/vocal) tic disorder, using DSM-5 criteria, (c)
with moderate or greater severity as measured by the YGTSS total score >13 (>9
for children with motor or vocal tics only).

Exclusion Criteria

Exclusion criteria (examined during intake interviews): (a) Behavioural
treatment for tics in the past 12 months, (b) pharmacological treatment (for
tics or diagnosed psychiatric disorders) that is not been stable the past six
weeks or with planned changes during study participation, (c) poor mastery of
the Dutch language, (d) IQ < 75, (e) serious physical disease, (f) substance
abuse, (g) suicidality, (h) psychotic disorders, (i) poor group functioning.
Since tic disorders are seldom seen without comorbidities, co-occurring
attention deficit-hyperactivity disorder, obsessive-compulsive disorder, other
anxiety disorders or depressive disorders are allowed, unless the disorder
requires immediate treatment or change in current treatment.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Assessments will be done pre- (T1), post-treatment (T2), and in follow-up<br /><br>assessments (T3 after 3-4 months and T4 after 6-7 months).<br /><br>Key-outcome: tic severity (Yale Global Tic Severity Scale; YGTSS) </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Demographic variables/patient characteristics: semi-structured interview ,<br /><br>medical files, psychiatric comorbidities (Anxiety Disorder Interview Schedule;<br /><br>ADIS).<br /><br>Secondary outcomes:<br /><br><br /><br>- quality of life (Gilles de la Tourette Syndrome Quality of Life Scale for<br /><br>children and adolescents; C&A-GTS-QOL).<br /><br>- emotional / behavioral functioning (Child Behavior Checklist; CBCL).<br /><br>- premonitory urges (Premonitory Urges for Tics scale; PUTS)<br /><br>- family functioning: parental stress<br /><br>- treatment alliance/preference<br /><br>- cost effectivity </p><br>