CTRI/2024/07/069904Not yet recruitingPhase 3 4
Comparative study of Haemodynamic parameters of Intravenous Oxytocin and Intravenous Carbetocin in patients undergoing Elective Caesarean section-One year Randomised Control Clinical Study
Dr Vanshika Saranga1 site in 1 country70 target enrollmentStarted: July 15, 2024Last updated:
Trial Snapshot
- Phase
- Phase 3 4
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 70
- Locations
- 1
- Primary Endpoint
- To compare the maternal hemodynamic changes for oxytocin and carbetocin(effect on heart rate and blood pressure)during elective Caesarean section
Study Overview
Brief Summary
This study is to compare haemodynamic responses following intravenous injection of oxytocin and carbetocin in patients undergoing elective caesarean section under subarachnoid block
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Participant Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 35.00 Year(s) (—)
- Sex
- Female
Inclusion Criteria
- •American Society of Anaethesiologists physical status II Patients undergoing elective caesarean section under subarachnoid block provides consent.
Exclusion Criteria
- •Presence of hypertension,preeclampsia,cardiac,renal or liver diseases, epilepsy and dearranged coagulation profile patients undergoing general anaesthesia and emergency LSCS patient who are unable or unwilling to give consent women with history of hypersensitivity to carbetocin patients who do not fulfil inclusion criteria.
Outcomes
Primary Outcomes
To compare the maternal hemodynamic changes for oxytocin and carbetocin(effect on heart rate and blood pressure)during elective Caesarean section
Time Frame: 0min,3min,6min,9min,12min,15min,18min,21min,24min,27min,30min,33min,36min,39min,42min,45min
Secondary Outcomes
- To assess the effective uterotonic action of oxytocin & carbetocin in terms of estimation of preoperative & postoperative HB estimation(48hours after delivery)
Investigators
Dr Vanshika Saranga
KLE Dr Prabhakar Kore Hospital and MRC
Study Sites (1)
Loading locations...
Similar Trials
Not yet recruiting
Phase 3
To Compare The Timing of Intravenous Oxytocin Administration To Minimize Blood Loss During First Trimester EvacuationCTRI/2025/07/091359SMIMS100
Not yet recruiting
Phase 2
Effects on vital parameters of drugs that stimulate uterine contractions like Oxytocin and carbetocin given as a bolus in a women undergoing caesarean deliveryCTRI/2024/03/064265Bangalore medical college and research institute60
Not yet recruiting
Unknown
Comparison of effect of two uterotonic drugs on hemodynamics and bleeding after cesarean section under spinal anesthesia.CTRI/2024/07/071700Department of Anesthesiology
Completed
Not Applicable
Comparison of the Effect of Carbetocin Versus Oxytocin in the Prevention of Postpartum Hemorrhage After Emergency Caesarean Section in Antenatal Low-risk PatientsNCT07380529Ankara Etlik City Hospital300
Completed
Phase 4
Carbetocin Versus Oxytocin and Hemodynamic EffectsEffects of Anesthesia, in PregnancyNCT00977769Oslo University Hospital76