Effect of high dose atorvastatin in preventing myocardial infarction following coronary angioplasty
Not Applicable
- Conditions
- Acute Myocardial Infarction.Acute myocardial infarction
- Registration Number
- IRCT201205209768N1
- Lead Sponsor
- Imam Khomeini hospital, Tehran University of MEdical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 190
Inclusion Criteria
Candidates for elective coronary angioplasty with stable angina at Imam Khomeini hospital.
Exclusion criteria::
1- Previous CABG
2- Need for emergency primary PCI (<2 hours)
3- Renal dysfunction
4- Hypersensitivity to statins
5- History of PCI
6- Histoty of valvular disease (regurgitation =>3+ or stenosis > 2 cm2
7- serum creatinine > 1.2 mg/dl
8- History of liver dysfunction or rise of hepatic aminotransferases>3 folds
9- ejection fraction<30%
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Myocardial infarction. Timepoint: 6 & 12 hours after angioplasty. Method of measurement: Serum levels of CK-MB and Troponin I.
- Secondary Outcome Measures
Name Time Method