Effects of Inspiratory Muscle Training in COPD

Phase 3

Completed

• Conditions: Inspiratory Muscle Weakness; COPD
• Interventions: Procedure: Inspiratory Muscle Training

• Registration Number: NCT01397396
• Lead Sponsor: KU Leuven

Brief Summary

The additional effect of inspiratory muscle training as an adjunct to a general exercise training program in patients with COPD with inspiratory muscle weakness will be studied. The main hypothesis is that inspiratory muscle training combined with an exercise training program improves functional exercise capacity more than an exercise training program without the addition of an inspiratory muscle training program.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2011-07-18
• Study First Submitted QC: 2011-07-18
• Study First Posted: 2011-07-19
• Study Start: 2012-02
• Primary Completion: 2016-12
• Study Completion: 2016-12
• Status Verified: 2017-03
• Last Update Submitted: 2017-03-12
• Last Update Posted: 2017-03-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 208

Inclusion Criteria

• Patients with COPD
• Eligible to participate in a exercise training intervention of 8 weeks
• Pi,max <60cmH2O or <50% of the predicted normal value

Exclusion Criteria

• Major comorbidities preventing successful participation in an 8 week exercise training intervention

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Sham IMT	Inspiratory Muscle Training	Sham Inspiratory Muscle Training
Inspiratory Muscle Training	Inspiratory Muscle Training	Inspiratory Muscle Training

Primary Outcome Measures

Name	Time	Method
6-Minute Walking Distance	Baseline and 8 weeks follow-up

Trial Locations

Locations (1)

University Hospital Leuven; 🇧🇪 Leuven, Belgium