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Can vaccination produce protective antibodies in people who fail to develop protective antibodies after recovery from COVID-19 infectio

Not Applicable
Conditions
Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
Registration Number
CTRI/2021/04/032572
Lead Sponsor
Rajiv Gandhi Cancer Institute and Research Centre
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

HCW

Employed at RGCI

Either sex

18-70 years

History of positive RT-PCR test for SARS-CoV-2

Either undetectable ( <1AU) or very low ( < 4.62 AU) IgG antibody titre

Vaccinated

Exclusion Criteria

Non Health Care Worker

Not an employee of Rajiv Gandhi Cancer Institute

Not vaccinated against COVID-19

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
IgG antibody titreTimepoint: 7-14 days post first dose of vaccination <br/ ><br>28 days post second dose of vaccination
Secondary Outcome Measures
NameTimeMethod
Any other symptomTimepoint: Post first dose of vaccination <br/ ><br>Post second dose of vaccination;ChillsTimepoint: Post first dose of vaccination <br/ ><br>Post second dose of vaccination;FeverTimepoint: Post first dose of vaccination <br/ ><br>Post second dose of vaccination;HeadacheTimepoint: Post first dose of vaccination <br/ ><br>Post second dose of vaccination;MalaiseTimepoint: Post first dose of vaccination <br/ ><br>Post second dose of vaccination;MedicationTimepoint: Post first dose of vaccination <br/ ><br>Post second dose of vaccination;MyalgiaTimepoint: Post first dose of vaccination <br/ ><br>Post second dose of vaccination;Pain at injection siteTimepoint: Post first dose of vaccination <br/ ><br>Post second dose of vaccination;RashesTimepoint: Post first dose of vaccination <br/ ><br>Post second dose of vaccination
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