Comparison between the effects of intravenous clonidine and dexmedetomidine on shivering after spinal anaesthesia
Phase 4
- Conditions
- Health Condition 1: 8- Other Procedures
- Registration Number
- CTRI/2020/09/027985
- Lead Sponsor
- Midnapore Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Age- 18-60 years
2. ASA grade 1 & 2
3. OT temp between 24 to 32 degree
4. Gynaecology and obstetrics, surgery, and
orthopaedic operations
Exclusion Criteria
1. Preexisting cardiac diseases
2. Pulmonary diseases
3. Bleeding or coagulation disorders
4. Renal or hepatic disease
5. Neuromuscular disorder
6. Psychiatric disorder
7. Hyperthyroidism
8. Deformity of the spinal column
9. Urinary tract infection
10.Severe diabetes or autonomic neuropathies
11.Known history of substance or alcohol abuse
12 Patient receiving any premedication
13.Cutaneous infection
14.Contraindication of spinal anaesthesia
15.Conversion to GA at any time intraoperatively
16.Patient refusal
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method We will compare the effects of clonidine and dexmedetomidine on shivering in terms of time of cessation of shivering, <br/ ><br>response rate and recurrence rate of shivering following spinal anaesthesia <br/ ><br>Timepoint: At baseline and at intervals of every 5 min for first 30 min and every 15 min for rest of the observation period after starting point of shivering.
- Secondary Outcome Measures
Name Time Method We will observe the change in blood pressure, heart rate, respiratory depression, nausea vomiting, dry mouth, effect of sedation in patients who will receive clonidine and dexmedetomidine separately.Timepoint: At baseline and at intervals of every 5 min for first 30 min and every 15 min for rest of the observation period after starting point of shivering.