Remission in Adults With Severe Asthma in Thailand
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 230
- 试验地点
- 1
- 主要终点
- Prevalence rate of severe asthma remission
研究概览
简要总结
The goal of this observational study is to determine the prevalence of remission among adults with severe asthma, as well as the factors associated with remission in Thailand.
The main question the study aims to answer is:
What is the prevalence of remission among adults with severe asthma in Thailand? Participants will complete questionnaires on asthma symptoms and undergo pulmonary function testing and a blood test once.
详细描述
This study is a cross-sectional study. Thai patients aged 18 years or older with severe asthma are included in the study. Participants will complete two questionnaires about asthma control: the Global Initiative for Asthma (GINA) and the Asthma Control Test (ACT), and will perform spirometry, a fractional exhaled nitric oxide (FeNO) test, and blood eosinophil counts (BEC).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •severe asthma
- •age 18 years or older
排除标准
- •inability to perform spirometry or fractional exhaled nitric oxide (FeNO) test
研究组 & 干预措施
Severe asthma
Asthma that requires treatment with high-dose inhaled corticosteroids plus a second controller, or requires systemic corticosteroids for ≥50% of the previous year to prevent it from becoming uncontrolled, or remains uncontrolled despite this therapy.
干预措施: Global Initiative for Asthma (GINA) and Asthma Control Test (ACT) questionnaires (Other)
Severe asthma
Asthma that requires treatment with high-dose inhaled corticosteroids plus a second controller, or requires systemic corticosteroids for ≥50% of the previous year to prevent it from becoming uncontrolled, or remains uncontrolled despite this therapy.
干预措施: Spirometry (Diagnostic Test)
Severe asthma
Asthma that requires treatment with high-dose inhaled corticosteroids plus a second controller, or requires systemic corticosteroids for ≥50% of the previous year to prevent it from becoming uncontrolled, or remains uncontrolled despite this therapy.
干预措施: Fractional exhaled nitric oxide (FeNO) test (Diagnostic Test)
Severe asthma
Asthma that requires treatment with high-dose inhaled corticosteroids plus a second controller, or requires systemic corticosteroids for ≥50% of the previous year to prevent it from becoming uncontrolled, or remains uncontrolled despite this therapy.
干预措施: Blood eosinophil count (BEC) (Diagnostic Test)
结局指标
主要结局
Prevalence rate of severe asthma remission
时间窗: The beginning of the study
Prevalence rate of remission in adults with severe asthma
次要结局
- Association of clinical characteristics with severe asthma remission(The beginning of the study)
- Association of lung function with severe asthma remission(The beginning of the study)
- Association of inflammatory biomarkers with severe asthma remission(The beginning of the study)
- Association of clinical characteristics with severe asthma remission(The beginning of the study)
- Association of lung function with severe asthma remission(The beginning of the study)
- Association of inflammatory biomarkers with severe asthma remission(The beginning of the study)
研究者
Narongkorn Saiphoklang, MD
Associate Professor
Thammasat University