d-LIVER - The Potential for Community Monitoring as a Tool to Improve Clinical Care and Patient Quality of Life in Advanced Liver Disease

• Conditions: K71.9; K72.1; Toxic liver disease, unspecified; Chronic hepatic failure

• Registration Number: DRKS00005308
• Lead Sponsor: Charité - Universitätsmedizin Berlin

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2013-09-16
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 387

Inclusion Criteria

Inclusion Criteria: - patient age >= 18 years - Biopsy proven cirrhosis - OR Suspected cirrhosis with existing complications like Varices, Ascites or Encephalopathy or increased liver tissue. - patients given written informed consent

Exclusion Criteria

Exclusion Criteria 1. Malignancy (excluding HCC) 2. Current antivirals for HCV

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The study will address the following specific question: What is the specific contribution made by the presence of the potentially treatable complications of ESLD encephalopathy and ascites to impairment of quality of life and function? The data in the literature suggest associations between the specific complications and impaired QOL, but does this suggest enhanced treatment for the complications would result in improved overall QOL

Secondary Outcome Measures

Name	Time	Method
-Influence of disease severity and actual liver function on HRQoL <br>-Identification of prognostic markers of short and longtime survival in patients with chronic liver disease<br>