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Clinical Trials/CTRI/2014/03/004453
CTRI/2014/03/004453
Recruiting
Phase 4

A randomized study of the cost effectiveness and tolerability of escitalopram and desvenlafaxine in treatment of moderate to severe depression

Moulya Nagraj0 sites60 target enrollmentTBD

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Health Condition 1: null- moderate depression
Sponsor
Moulya Nagraj
Enrollment
60
Status
Recruiting
Last Updated
4 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
4 years ago
Study Type
Interventional

Investigators

Sponsor
Moulya Nagraj

Eligibility Criteria

Inclusion Criteria

  • Subjects of either gender aged between 18\-65 years.
  • Subjects with first episode or recurrent episode of depression according to (ICD\-10\) with baseline score \>18 and \< 40 according to MADRS.
  • Willingness to give written informed consent and available for follow up.

Exclusion Criteria

  • Atypical depression
  • Postpartum depression
  • Pregnant women, breast feeding and women planning to conceive.
  • Subjects with severe depression requiring ECT and with high risk of suicidal tendency.
  • Co\-morbid psychiatric illnesses
  • Previous history of epilepsy and sexual dysfunction
  • Serious or uncontrolled medical illness like glaucoma, hypertension, diabetes mellitus, hyperlipidemia, myocardial infarction, hepatic and renal impairment.
  • Depression secondary to medical illnesses, post traumatic depression.
  • Known history of allergy to both the study medications.
  • Participation in any other research study in recent past

Outcomes

Primary Outcomes

Not specified

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