Effects of Mineralocorticoid Receptor Stimulation on Cognition

Not Applicable

Completed

• Conditions: Individuality
• Interventions: Other: Fludrocortisone

• Registration Number: NCT02478034
• Lead Sponsor: Charite University, Berlin, Germany

Brief Summary

In this study the effects of mineralocorticoid stimulation on social cognition will be investigated in healthy young individuals.

Detailed Description

80 healthy young individuals (40 females and 40 male) will be recruited an randomized to either placebo or 0.4 mg Fludrocortison before testing. Tasks will on emotion recognition, Task Switch, visual spacial memory and decision making will be conducted.

Study Timeline

• Study Start: 2015-05
• Study First Submitted: 2015-06-11
• Study First Submitted QC: 2015-06-18
• Study First Posted: 2015-06-23
• Status Verified: 2016-03
• Primary Completion: 2016-03
• Study Completion: 2016-03
• Last Update Submitted: 2016-03-04
• Last Update Posted: 2016-03-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• free of medication
• age 18 - 30

Exclusion Criteria

• any medication
• severe illness

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Placebo	Fludrocortisone	effects of fludrocortisone on cognition compared to placebo
fludrocortisone	Fludrocortisone	effects of fludrocortisone on cognition compared to placebo

Primary Outcome Measures

Name	Time	Method
social cognition	25 min	computer based tests: emotion recognition

Secondary Outcome Measures

Name	Time	Method
memory	20 min	computer based test on visuospacial memory
decision making	25 min	computer based tests: BART

Trial Locations

Locations (1)

Charite University; 🇩🇪 Berlin, Germany