The Value of DWI-MRI(Diffusion-weighted Imaging) in Evaluating the Early Efficacy of Liver Metastasis in Colorectal Cancer

Fudan University1 site in 1 country100 target enrollmentAugust 2016

ConditionsDWI-MRI

Overview

Phase: N/A
Intervention: Not specified
Conditions: DWI-MRI
Sponsor: Fudan University
Enrollment: 100
Locations: 1
Primary Endpoint: Response rate
Last Updated: 9 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The study is designed to evaluate the value of DWI-MRI (Diffusion weighted magnetic resonance imaging) in predicting the efficacy of liver metastases after chemotherapy in colorectal cancer.

Registry

clinicaltrials.gov

Start Date

August 2016

End Date

August 2018

Last Updated

9 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Fudan University

Responsible Party

Principal Investigator

Weijian Guo

Fudan University Shanghai Cancer Center

Fudan University

Eligibility Criteria

Inclusion Criteria

•aged ≥18 years with histologically or cytologically confirmed advanced colorectal adenocarcinoma
•Eastern Cooperative Oncology Group performance status of 0 to 2
•life expectancy of ≥ 3 months
•at least one measurable liver metastatic lesion in MRI (≥10mm)
•have adequate bone marrow, hepatic, and renal function
•previously received no palliative chemotherapy

Exclusion Criteria

•patients with previous chronic inflammatory bowel disease, chronic diarrhea or recurrent bowel obstruction
•patients with symptomatic brain metastases
•active clinical severe infection
•have contraindication of MRI screening