The use of a randomised controlled trial of autologous stem cell transplantation (ASCT) versus mobilisation alone to investigate the pathogenic role of T-cells in patients with severe rheumatoid arthritis
Completed
- Conditions
- Musculoskeletal Diseases: Rheumatoid arthritis (RA)Musculoskeletal Diseases
- Registration Number
- ISRCTN52892553
- Lead Sponsor
- Record provided by the NHS Trusts Clinical Trials Register - Department of Health (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients with rheumatoid arthritis who have failed conventional therapy. Patients will be enrolled from specialist RA clinics.
Exclusion Criteria
Not provided at time of registration
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method RA quality of life questionnaire, health assessment questionnaire. Tender and swollen joint counts. Inflammatory markers. Histological analysis.
- Secondary Outcome Measures
Name Time Method ot provided at time of registration