Clinical study on the relationships between disease progression and inflammation in retinitis pigmentosa

Not Applicable

Recruiting

• Conditions: Retinitis pigmentosa; Inherited retinal dystrophy; D012174

• Registration Number: JPRN-jRCT1070210092
• Lead Sponsor: Sonoda Koh-Hei

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-11-09
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

(1) Patients diagnosed as typical retinitis pigmentosa (genetic diagnosis is unnecessary)
(2) Patients who understand the design/purpose of the study and have the ability to declare consent by her/himself
(3) Patients whose age is 20-70 at the time of informed consent
(4) Patients whose mean retinal sensitivity within the central 4 degree area (central 12 points) is 10 dB or above in the Humphery 10-2 perimetry test
(5) Patients whose central foveal thickness is 250 micrometer or less in the OCT measurement

Exclusion Criteria

(1) Patients with anemia (Hb: 8g/dl or less)
(2) Patients who are in poor general condition (PS: 3 or above)
(3) Patietns with glaucoma or ocular hypertension (Intraocular pressure: 22 mmHg or above)
(4) Patients with uveitis or optic neuritis
(5) Patients with retinal disorders (e.g. retinal hemorrhage, retinal edema, proliferative tissue) that are not related with retinitis pigmentosa
(6) Patients with severe systemic complications
(7) Patients who are judged ineligible for the study by investigators

Study & Design

• Study Type: Observational
• Study Design: Not specified