Prediction of Fluid Responsiveness From Passive Leg Raising Induced Changes in Perfusion Index and Pleth Variability Index
- Conditions
- Fluid Responsiveness
- Registration Number
- NCT03499860
- Lead Sponsor
- Institute of Mountain Emergency Medicine
- Brief Summary
The aim of the study is to evaluate whether changes in Perfusion Index (PI) and Pleth Variability Index (PVI) during passive leg raising test can predict fluid responsiveness in spontaneously breathing patients.
Fluid responsive patients are defined as showing an increase in cardiac output \>10% during a passive leg raising test, measured semi-invaseively with FloTrac® (Edwards LifeSciences. Irvine, United States).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 51
- Adult patients admitted to the intensive or intermediate care unit after abdominal surgery (including urological and gynecological surgery performed in laparotomy)
- Spontaneous breathing
- Arterial line already in place
- Oral and written informed consent obtained
- Age <18 years
- Abdominal trauma as the reason for surgery
- Missing informed consent
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method PI difference 90 seconds Difference in the change of perfusion index from baseline during a passive leg raising maneuver in fluid responsive patients compared to fluid non-responders
PVI difference 90 seconds Difference in the change of pleth variability index from baseline during a passive leg raising maneuver in fluid responsive patients compared to fluid non-responders
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
"F. Tappeiner" Hospital Merano
🇮🇹Merano, Bolzano, Italy