Respirophasic Carotid Artery Peak Velocity Variation as a Predictor of Fluid Responsiveness in Patients With Coronary Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Predictive power of the respirophasic carotid flow peak velocity variation for the fluid responsiveness
研究概览
简要总结
The aim of this study is to investigate usefulness of the respirophasic variation in carotid artery peak flow velocity measured by Doppler ultrasound, which is noninvasive and easily accessible, as a predictor of fluid responsiveness in patients with coronary artery disease.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients scheduled for elective isolated off-pump coronary artery bypass graft surgery
排除标准
- •cardiac rhythm other than sinus
- •congestive heart failure
- •left ventricular ejection fraction <35%
- •history of transient ischemic attack
- •pre-existing cerebrovascular disease and peripheral arterial occlusive disease
- •presence of carotid artery stenosis >50%
研究组 & 干预措施
fluid responsiveness
干预措施: Volume expansion (Other)
结局指标
主要结局
Predictive power of the respirophasic carotid flow peak velocity variation for the fluid responsiveness
时间窗: Measurement of respirophasic carotid flow peak velocity variation before the volume expansion
After induction of anesthesia, peak velocity of carotid artery blood flow is measured by the pulsed wave Doppler signal obtained from the left common carotid artery. Respirophasic variation of the peak velocity is defined as the difference between the maximum and the minimum values of peak velocity divided by the mean of the two values during one respiratory cycle. Fluid responder is defined as a patient whose stroke volume index is increased ≥15% after volume expansion. The receiver operating characteristic curve analysis to descriminiate fluid responder is performed.
次要结局
未报告次要终点