Comparison of the efficacy of oral Acetaminophen and intravenous Acetaminophen for closure of patent ductus arteriosus in preterm neonates
Phase 3
Recruiting
- Conditions
- Patent ductus arteriosus (PDA).Patent ductus arteriosusQ25.0
- Registration Number
- IRCT20190505043478N1
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Written parental consent is obtained
Gestational age 26 to 37 weeks
Diagnosis of ductus arteriosus based on echocardiographic evidence at 24 to 72 hours after birth
Exclusion Criteria
No Parental consent
Any congenital heart disease with the need to PDA to keep blood flow constant ( Based on patient records).
Life threatening infections .( Based on patient records)
Liver Disease
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method PDA size. Timepoint: The neonates receives echocardiography before and after treatment. Method of measurement: Patient PDA evaluated before and after treatment, based on severity of the disease, and findings of the echocardiography by pediatiric's cardiologist .
- Secondary Outcome Measures
Name Time Method