Observing the Perioperative Effects of Prehabilitation in Colorectal Cancer
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- Length of stay
研究概览
简要总结
Quality Improvement Project to evaluate how prehabilitation can be incorporated into our colorectal cancer pathway and assess its clinical benefits.
详细描述
The aim was to evaluate how prehabilitation (PH) can be incorporated into our colorectal cancer pathway and assess its clinical benefits.
Patients underwent PH (exercise, nutrition and psychological support) before resection of colorectal carcinoma in a DGH over fourteen months. Patients were matched by operation, age, sex and ASA to non-prehabilitation (NPH) patients using a prospectively maintained database. Length of stay (LoS) and complication rate and 90-day readmission rates were compared using Wilcoxon and McNemar's methods.
Prehabilitation significantly improved peak VO2 and AT. This corresponds to a reduction in predicted 30-day mortality. Despite a higher Charlson index LoS was unchanged suggesting prehabilitation may permit safe resection in comorbid patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults over the age of 18 who had prehabilitation for colorectal cancer
排除标准
- •Patients who had prehabilitation but not for colorectal cancer
结局指标
主要结局
Length of stay
时间窗: From date of operation to date of discharge in number of days over a 90 day follow up period
Time spent in hospital
Complication rate
时间窗: Follow up over a period of 90 days following operation
All Clavien-Dindo complications
次要结局
- Anaerobic threshold(CPET performed before prehabilitation and after prehabilitation (median of 36 days))
研究者
Richard Dickson-Lowe
Consultant Surgeon
Medway Primary Care Trust