The Use of Perfusion CT Derived Parameters as Early Acute Pancreatitis Severity Biomarker Compared to Clinico Biological Score
- Conditions
- Acute Pancreatitis
- Interventions
- Radiation: Perfusion computed tomography.
- Registration Number
- NCT03456557
- Lead Sponsor
- Poitiers University Hospital
- Brief Summary
The investigators to establish whether early microvascular permeability parameter evaluated by perfusion-CT could be good biomarkers for severity in acute pancreatitis.
Therefore the investigators want to compare 48 hours-clinico-biological systemic inflammatory response syndrome score to initial microvascular permeability parameters ( ktrans - capillary membrane permeability factor- and pancreatic blood flow ) calculated by OLEA software using inclusion perfusion CT.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 15
- Patient with acute pancreatitis (based on the Atlanta definition).
- Patient under 18 yearras old
- Contraindication of injection of iodinated contrast medium
- Pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Computed tomography. Perfusion computed tomography. -
- Primary Outcome Measures
Name Time Method Relation between CT perfusion calculated k-trans and clinicobiological SIRS score in early phase of acute pancreatitis. admission day
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Chu de Poitiers
🇫🇷Poitiers, France