Reconsolidation: a new intervention towards combat-related PTSD.
Completed
- Conditions
- posttraumatic stress disorder | trauma10002861
- Registration Number
- NL-OMON55097
- Lead Sponsor
- TNO
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 8
Inclusion Criteria
1. aged between 18 and 65 years
2. a primary diagnosis of PTSD according to DSM-5, resulting from
combat-related trauma(s)
3. a score of > 20 on the Posttraumatic Symptom Scale at screening
Exclusion Criteria
1. other relevant treatment for PTSD within 3 months before start of the study
2. start of new medication within 3 months before start of study
3. life-time psychosis
4. acute suicide risk
5. current state of asthma or COPD, which necessitates medication use
6. cardiovascular diseases or irregular heartbeat
7. hypotension or hypertension
8. pregnancy or breastfeeding
9. epilepsy
10. any medication contra-indicative of the use of propranolol
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Our primary output will be (a) the percent change in PTSD diagnosis and (b) the<br /><br>decrease in frequency and severity of PTSD symptoms, from baseline to<br /><br>post-treatment and follow-up.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Not applicable.</p><br>