Multicentric study to evaluate potential vessel damage in patients suffering from Thalidomide brth defect (Contergan)
Recruiting
- Conditions
- Q27Other congenital malformations of peripheral vascular system
- Registration Number
- DRKS00030210
- Lead Sponsor
- niversitätsklinikum Köln
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 804
Inclusion Criteria
patients, registered by Contergan foundation with an underlying malfunction or disability caused by Thalidomide; healthy volunteers
Exclusion Criteria
known contraindication for assessment by MRI; pregnancy; Body weight higher than 150 kg; Claustrophobia
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Registration of frequency and kind of Organ- and Vesselanomaly, as well as assessment of diameter of the vessels in patiente suffering from Thalidomide induced deficiencies.
- Secondary Outcome Measures
Name Time Method MRI assessment of cardial anomaly; US assessment of arteriosclerotic changes; Assessment of severitiy of Hypertonia; blood/urine assessment; Diameter and alteration of vessels in comparison to healthy volunteers.