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Clinical Trials/NCT06497205
NCT06497205
Recruiting
Not Applicable

AMBulatory Fetal ECG Monitoring in Low and High-Risk Pregnancies

Biorithm Pte Ltd1 site in 1 country180 target enrollmentMarch 19, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pregnancy Related
Sponsor
Biorithm Pte Ltd
Enrollment
180
Locations
1
Primary Endpoint
FHR
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

This study is a planned research project to test and demonstrate the feasibility of using the Femom device for monitoring fetal heart rate remotely.

The main goal is to learn if the remote recordings using Femom provide reliable information about the baby's heart rate. We will also establish reference standards of heart rate variability in uncomplicated pregnancies at different stages of pregnancy. Additionally, we will compare the heart rate variability in FGR and diabetic pregnancies to normal pregnancies.

Detailed Description

The Femom device is a non-invasive fetal ECG (NIFECG) device which has been developed for self application and remote monitoring. Women from three different cohort groups (controls, FGR and insulin dependent diabetes) will be approached and asked to monitor their baby at home once a day. Women in the control group will be asked to do this once a day for one week, the FGR pregnancies until delivery and the insulin dependent diabetics just from 36 weeks until delivery. The data will be collected and analysed retrospectively to assess compliance of the participants with the study protocol, signal quality and establish reference standards in relation to gestation within the control group. Heart rate variability measures in the FGR and diabetes arm will be compared to the reference standards in the control group. Outcomes of the pregnancy. Feedback regarding the usability of the device will also be collected using a feedback questionnaire to assess the feasibility of home antenatal monitoring.

Registry
clinicaltrials.gov
Start Date
March 19, 2024
End Date
August 31, 2025
Last Updated
last year
Study Type
Observational
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Singleton live pregnancy
  • \> 26 weeks gestational age
  • Able to speak English or available NHS interpreter

Exclusion Criteria

  • Women below 18 years of age
  • Women with an intellectual or mental impairment
  • Women with a known allergy or hypersensitivity to ECG gel electrodes
  • Known fetal cardiac or genetic abnormality.
  • Patient with existing dependent or unequal relationships with any member of the research team, the researchers(s) and/or the person undertaking the recruitment/consent process.
  • Inability to access interpreter.

Outcomes

Primary Outcomes

FHR

Time Frame: 60 minutes

FHR agreement between Femom system and standard of care (CTG)

MHR

Time Frame: 60 minutes

MHR agreement between Femom system and standard of care (CTG)

Study Sites (1)

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