The Evaluation of Infertility and Pregnancy Outcomes, as Well as the Assessment of Quality of Life Using WHOQoL and FertiQoL, in Cases of Gynecological Malignancies That Have Undergone Fertility-sparing Surgery(FSS)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Fertility Disorders
- Sponsor
- Acibadem University
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Incidence of pregnancy of patients received FSS
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
FSS which aims to preserve a woman's fertility while still effectively treating the cancer, has become an increasingly popular option for young women diagnosed with these types of cancers. It is important to assess how FSS affects a woman's reproductive health, sexual function, psychological well-being, and overall quality of life. This research aims to provide valuable insights into the long-term effects of FSS on a woman's life, and can help healthcare providers make informed decisions about the best treatment options for their patients.
Detailed Description
This is a prospective cohort study that aims to evaluate the infertility and pregnancy outcomes, as well as the quality of life of women who underwent fertility-sparing surgery for gynecological malignancies. The study included a comprehensive evaluation of the participants' medical history, surgical procedures, oncological treatment, and fertility preservation methods. Participants recruited from a tertiary care hospital, and women diagnosed with gynecological malignancies (e.g. cervical, ovarian, endometrial cancer) who underwent fertility-sparing surgery between 2010 and 2022. Women who have undergone total hysterectomy, bilateral salpingo-oophorectomy, or adjuvant oncological treatment were excluded from the study. Participants were contacted by phone and asked to complete questionnaires to assess their quality of life using the WHOQoL-BREF and FertiQoL scales.
Investigators
Nazli Albayrak
PGY-4 Ob/Gyn resident, MD
Acibadem University
Eligibility Criteria
Inclusion Criteria
- •Diagnosis of gynecologic cancer, and being fertile in the meantime
- •Applying directly to gynecologic oncology department
- •Demand of preserving the fertility
Exclusion Criteria
- •Having hysterectomy prior to the diagnosis
- •Having bilateral ooferectomy prior to the diagnosis
- •Being in menopause
- •Not accepting to fill the survey
- •High stage disease which is not able to have FSS
Outcomes
Primary Outcomes
Incidence of pregnancy of patients received FSS
Time Frame: In 12 years after FSS
Incidence and rate of patients getting pregnant after FSS
Rate of pregnancy after FSS of patients seeking fertility by applying to IVF clinics
Time Frame: In 12 years after FSS
Rate of patients referring to IVF clinic after FSS
Secondary Outcomes
- Satisfaction assesed by WHO-QoL Bref and decision-regret scale after FSS(12 years)