Effects of Soluble Phosphate in Humans
Not Applicable
Completed
- Conditions
- Healthy Volunteers
- Registration Number
- NCT02095392
- Lead Sponsor
- University of Jena
- Brief Summary
The study was conducted to investigate the effect of soluble phosphate in combination with different calcium doses on calcium and phosphorus metabolism and further physiological parameters in healthy subjects. The main aim of the study is to investigate the influence of a soluble phosphate supplementation on the fasting blood phosphate concentration and the dependency of an additional calcium intake.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 62
Inclusion Criteria
- age between 18-60 years
- physical health
Exclusion Criteria
- postmenopausal women
- kidney diseases
- diabetes mellitus
- metabolic diseases
- osteoporosis
- intake of dietary supplements
- pregnancy and lactation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Fasting phosphate concentration in blood 8 weeks
- Secondary Outcome Measures
Name Time Method Calcium and phosphorus metabolism 8 weeks * parameters of phosphate and calcium metabolism (1,25-OHD; 25-OHD;FGF23;PTH)
* parameters of bone formation and resorption (osteocalcin, P1NP, CTX)
* minerals in plasma, faeces and urine
Trial Locations
- Locations (1)
Friedrich-Schiller-University Jena, Institute of Nutrition, Department of Nutritional Toxicology
🇩🇪Jena, Thuringia, Germany
Friedrich-Schiller-University Jena, Institute of Nutrition, Department of Nutritional Toxicology🇩🇪Jena, Thuringia, Germany