Analgesic Efficacy of Erector Spinae Plane Block After Breast Cancer Surgery
- Conditions
- Postoperative PainBreast Cancer
- Interventions
- Procedure: Ultrasound guided Erector Spinae Plane Block (ESPB)
- Registration Number
- NCT04512391
- Lead Sponsor
- TC Erciyes University
- Brief Summary
Erector spinae plane block(ESPB), which is firstly used for thoracic neuropathic pain, is newly developed and highly promising fascial plane block for providing postoperative analgesia for a great deal of surgeries including breast surgery. The investigators aim to study efficacy of ESPB for patients who undergone breast cancer surgery and is expected to benefit from opioid-sparing effect of this technique.
- Detailed Description
This is a retrospective, single-center clinical trial to evaluate analgesic efficacy of Erector spinae plane block (ESPB) after breast cancer surgery. Participant's demographics and medical history, type and extent of surgery, systemic opioid and non-opioid analgesic consumptions, hemodynamic variables and adverse events during and first 24 hours after surgery. After operation, pain scores at first 24 hours, 1., 3., and 6. month will be obtanied from surgical ward and pain clinic registires. patient controlled analgesia device usage history will be obtained from device database at our clinic.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 40
- ASA I-II patients undergoing breast surgery for breast cancer
- Becoming available of complete records about study data
- ASA III-IV patients
- missing records about study data
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Erector Spinae Ultrasound guided Erector Spinae Plane Block (ESPB) patients who are administered ultrasound guided ESPB at T4 vertebrae level with long acting local anesthetic (%0,25 bupivacaine) and followed up with patient controlled analgesia device and all records about aforementioned data is completely available.
- Primary Outcome Measures
Name Time Method Opioid Consumption First 24 hours after surgery all patients were given 0.05 mg/kg morphine iv and 1 gr paracetamol 30 minutes before end of surgery and in the recovery room, a patient- controlled analgesia device containing morphine 0.5 mg/ml, set to deliver a 1mg bolus dose of morphine with an 10 min lockout time. Total morphine consumption during the 24 hours postoperative period will recorded at 5 times intervals ( 2, 4, 6, 12, 24 hours).
Verbal Analog Pain Scores on rest and movement First 24 hours after surgery, at 1., 3., 6. month A Research assistant, blinded to the group allocation, interviewed patients and collected data at 5 times intervals ( 2, 4, 6, 12, 24, hours) in the 24 hours postoperatively. Patients were asked to rate their pain using verbal analog scale, where 0= no pain and 10= worst pain possible.
- Secondary Outcome Measures
Name Time Method Demographic Data First 24 hours after surgery Age, sex, medical history, BMI, ASA (American Society of Anesthesiologists) status, Duration and type of surgery were recorded
Blood Pressures during and first 24 hours after surgery systolic, diastolic and mean arterial blood pressures as mmHg
Heart Rate during and first 24 hours after surgery Heart rate as beat per minute (BPM)
incidence of adverse effects (like nausea and vomiting) First 24 hours after surgery incidence of nausea and vomiting during the 24 hours postoperative period was recorded recorded at 5 times intervals ( 2, 4, 6, 12, 24 hours)
Rescue analgesic requirement First 24 hours after surgery number of request and dosages of non opioid analgesics used for VAS equal or greater than 5 or patient request.
Trial Locations
- Locations (1)
TC erciyes university
🇹🇷Kayseri, Melikgazi, Turkey