跳至主要内容
临床试验/CTRI/2025/03/083712
CTRI/2025/03/083712招募中不适用

Comparison of Image Quality in Low Dose , Low Contrast Computed Tomography Coronary Angiogram Reconstructed With Filtered Back Projection and Iterative Reconstruction Algorithm

Not Appilicable1 个研究点 分布在 1 个国家目标入组 76 人开始时间: 2025年4月22日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
76
试验地点
1
主要终点
The significance of this research lies in its potential to improve the efficacy and safety of coronary computed tomography angiography (CCTA) By reducing radiation exposure and contrast agent use.

研究概览

简要总结

·       After all the approvals sample size screening will be executed with respect to    inclusion and exclusion criteria.

·       All the procedure will be explained to the patient and breath bold instructions should be given and heart rate should be monitored.

·       All the demographic details will be collected.

·       Scan will perform using the standard operating protocol

·       The best cardiac phase with least motion artifact will be reconstructed with respect to  R-R interval.

·       The best Phase will be selected and reconstructed using filtered back and iterative (idose  level 3) reconstruction algorithm  by keeping the filter CB constant

·       All the images will be then transferred to ISP server for image analysis.

·       Image will be analysed qualitatively and quantitively. For quantitative analysis ROI will be placed LM, RCA, LAD, LCX and Major branch to calculate CNR, SNR and image noise.

·       For qualitative analysis images will be accessed by two Radiologist without revealing the reconstruction technique to access image quality.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • Age range 18-80 Years All sexes All the patients referred for CT Coronary Angiography Ability to sustain a Breath hold for minimum of 8-10 Sec.

排除标准

  • Patient with high BMI CABG Cases Coronary Stents.

结局指标

主要结局

The significance of this research lies in its potential to improve the efficacy and safety of coronary computed tomography angiography (CCTA) By reducing radiation exposure and contrast agent use.

时间窗: 12 months (February 2025-February 2026)

With a comparative analysis of different reconstruction techniques. This research aims to find the optimal reconstruction method to achieve high image quality in a low-dose protocol. This provides important insights for improving CT coronary angio.

时间窗: 12 months (February 2025-February 2026)

次要结局

  • Not Applicable(Not Applicable)

研究者

发起方
Not Appilicable
申办方类型
Other [na]
责任方
Principal Investigator
主要研究者

SACHIN DINAKARA NAIK

Manipal College of Health Professions

研究点 (1)

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