Golgi Protein for HCC Diagnosis
Completed
- Conditions
- Screening for Hepatocellular Carcinoma
- Interventions
- Diagnostic Test: Serum Golgi Protein 73
- Registration Number
- NCT03039322
- Lead Sponsor
- Ain Shams University
- Brief Summary
This case-control study was conducted on 90 patients who were equally divided into two groups. Group 1 included 45 patients with HCV-related chronic liver disease without clinical or radiological evidence of HCC (control group), and Group 2 included 45 patients diagnosed to have HCC by Triphasic abdominal CT (patient group). Serum AFP and GP73 were measured using ELISA technique
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
- patients were older than 18 years.
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Exclusion Criteria
- patients with hepatic focal lesions not due to HCC such as Hemangioma, Hepatic cyst, and liver metastases; patients infected with HIV; patients with any autoimmune disease; or patients with metastatic disease.
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description liver cirrhosis No HCC Serum Golgi Protein 73 - HCC Serum Golgi Protein 73 -
- Primary Outcome Measures
Name Time Method Golgi protein correlated with presence of HCC within one year
- Secondary Outcome Measures
Name Time Method