NL-OMON55979
Recruiting
Not Applicable
Exercise training in women with unexplained recurrent pregnancy loss to optimize receptive endometrial NK cell population and function - HMove
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- reproductieve immunologie
- Sponsor
- Radboud Universitair Medisch Centrum
- Enrollment
- 100
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Women with two or more unexplained pregnancy losses, defined as women without
- •uterine abnormalities, antiphospholipid syndrome, thyroid abnormalities and
- •abnormal parental karyotyping if indicated according to international
- •Couples should not be aiming to conceive during the time course of the exercise
- •intervention.
Exclusion Criteria
- •\-Age above 40 years
- •\-Use of immunosuppressive drugs, biological or antidepressants
- •\-Use of hormone conceptive
- •\-HIV positivity
- •\-Current or recent (\<2 weeks) symptomatic genital infection such as chlamydia,
- •gonorroa, or pelvic inflammatory disease
- •\-Pre\-existent diabetes mellitus, autoimmune disease or overt cardiovascular
- •\-Smoking or use of medication or supplements that might affect the
- •cardiovascular system
- •\-Vaccination (i.e Covid) within 3 months prior to or during sampling and
Outcomes
Primary Outcomes
Not specified
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