Effects of Hydroalcoholic Extract of Black Barberry Fruit in Active Rheumatoid Arthritis Patients

Phase 3

Completed

Conditions: Active rheumatoid arthritis.
Other specified rheumatoid arthritis

Registration Number: IRCT201510259472N8

Lead Sponsor: vice-chancellor for research, Iran University of Medical Science

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 80

Inclusion Criteria

person with RA disease as American College of Rheumatology (ACR) criteria; age between 18-69 years; having RA from 1 years ago; active rheumatoid arthritis; acceptance of patient; not having diabetes mellitus, hypertension, thyroid problem, renal failure and liver dysfunction; not smoking; not being pregnant or lactated; not receiving omega-3 or antioxidants supplements from 3 month ago; not getting contraceptive drugs; exclusion criteria: reluctance for continuing the cooperation ; taking less than 80% of supplements given to patients at baseline (the compliance lower than %80); sudden strickening to an acute disease; migration ; any change in drug and treatment protocol that can cause omission from study.

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
IL2. Timepoint: First day and three months later. Method of measurement: Elisa.;IL4. Timepoint: First day and three months later. Method of measurement: Elisa.;IL10. Timepoint: First day and three months later. Method of measurement: Elisa.;IL17. Timepoint: First day and three months later. Method of measurement: Elisa.

Secondary Outcome Measures