Preventing pneumococcal disease in people without spleens (asplenia) and with poorly functioning spleens (hyposplenia)

Phase 4

• Conditions: Improving and sustaining pneumococcal antibodies in asplenic patients; Better understanding of pneumococcal vaccine regimes in asplenic/hyposplenic patients; Asplenia and Hyposplenia; Infection - Other infectious diseases; Public Health - Health service research; Infection - Studies of infection and infectious agents

• Registration Number: ACTRN12610000210077
• Lead Sponsor: ational Health and Medical Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-03-15
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 250

Inclusion Criteria

People with a histroy of splenectomy (asplenia) and those with a diagnosis of hyposplenism that is confirmed by presence of Howell Jolly bodies (HJBs) on blood film. To participate in trial patients must be over 10 years of age.

Exclusion Criteria

STUDY PARTICIPANTS: Patients who (i) could not comply with study commitments (ii) receiving cancer therapy, (iii) received pneumococal polysaccharide vaccine in previous three years

Study & Design

• Study Type: Interventional
• Study Design: Not specified