Management of Manasika Avasaada with Kushmanda ghrita either by Nasya or Pana

Phase 2

Not yet recruiting

• Conditions: Patient diagnosed with Vishaada

• Registration Number: CTRI/2017/12/010866
• Lead Sponsor: IPGT and RA

Brief Summary

The study comprises a Comparative Clinical study to evaluate the efficacy of Nasya  and Pana with Kushmanda ghrita in the management  of Vishaada with special reference to Depression. As Vishaada  mentioned in Ayurvedic classics as a Vataja Vyadhi  affects monobaha srotas mainly. So Kushmanda as Nasya n Pana   planned for Vishaada.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2017-12-12
• Study Start: 2018-01-19

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• The patient of Mild and Moderate Depressive disorder at least two (but less than five) of the following symptoms will be included in this study (1 ) Marked loss of interest or pleasure in activities that are normally pleasurable (2) Lack of emotional reactions to events or activities that normally produce an emotional response (3) Waking in the morning 2 hours or more before the usual time (4) Depression worse in the morning (5) Objective evidence of marked psycho motor retardation or agitation (remarked on or reported by other people) (6) Marked loss of appetite (7) Weight loss (5% or more of body weight in the past month) (8) Marked loss of libido 2.
• AGE 18 to 60 years of either sex 3.
• Chronicity less than 2 years.

Exclusion Criteria

1.Age- Below 18 years and above 60 years 2.Anxiety obsessive compulsive disorders 3.Toxic causes like Alcohol ingestion and withdrawal 4.Organic diseases like some diseases of Gastrointestinal system for example irritable bowel syndrome or Colitis 5.Myocardial Infarction 6.CNS diseases for example Alzeimer disease metabolic disorder and Endocrine disorders etc 7.Major Depressive Disorders 8.Patients superimposed with Schizophrenia schizophreniform disorders mania Bipolar disorders as psychotic disorder not otherwise specified 9.Patients suffering from chronic drug abuse for example barbiturates etc 10.Mood incongruent delusions or hallucinations or marked loosening of associations Patients suffering from chronic drug abuse.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hamilton Rating Scale of Depression	45 days
BECKs Depression Inventory	45 days
ICD-10	45 days

Secondary Outcome Measures

Name	Time	Method
Improve life quality of patient	45 days

Trial Locations

Locations (1)

PG Hospital IPGT and RA; 🇮🇳 Jamnagar, GUJARAT, India

PG Hospital IPGT and RA

🇮🇳Jamnagar, GUJARAT, India

Sabari Sengupta

Principal investigator

9433823717

sabari.sengupta68@gmail.com