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临床试验/NCT05213923
NCT05213923已完成不适用

ED Tracking Sheet Implementation

Dartmouth-Hitchcock Medical Center2 个研究点 分布在 1 个国家目标入组 194 人开始时间: 2021年7月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
194
试验地点
2
主要终点
Percentage of goal-directed sepsis criteria met

研究概览

简要总结

The purpose of this study is to assess whether implementation of an ED Sepsis Tracking Sheet effects the percentage of goal-directed sepsis criteria met in a tertiary care academic Emergency Department.

详细描述

Sepsis remains a common cause of morbidity and mortality in the hospital setting. Accurate diagnosis and timely initiation of therapy are important drivers of patient-centered outcomes in sepsis management. Compliance with the core measures listed in the surviving sepsis campaign guidelines has been variable.

An ED-specific Sepsis Tracking Sheet (STS) - a tool for implementing and documenting critical actions in sepsis management - was created at our institution by a team of physicians, nurses, and ED pharmacists. Dedicated ED pharmacists were instructed to fill this sheet within one hour of the sepsis-specific best practice advisory (BPA) being activated in the ED. Core measures associated with the one hour and three hour sepsis bundles were tracked and outcomes were compared pre- and post-implementation of the STS.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Over 18 years old
  • Initially evaluated in the DHMC Lebanon Emergency Department
  • Activated sepsis BPA upon initial presentation (triage history consistent with infection combined with 2 or more SIRS criteria? Are these the criteria that trigger our sepsis BPA?)

排除标准

  • Patients who are transferred to the DHMC Lebanon Emergency Department from another facility
  • Patients with absent data regarding one or more of the goal-directed sepsis criteria
  • Patients who did not initially meet criteria to trigger the sepsis BPA, but developed sepsis later in their hospital course

结局指标

主要结局

Percentage of goal-directed sepsis criteria met

时间窗: Time of ED presentation to the time of in-hospital death or hospital discharge, approximately 2 weeks

Goal-directed sepsis criteria involve the following: 1) Was an initial lactate obtained? 2) Were two sets of blood cultures sent? 3) Were antibiotics given within one hour of identification of severe sepsis? 4) Was the patient given an initial IV fluid bolus? 5) Was a repeat lactate sent if the initial lactate was elevated? These five criteria will be assessed as "met" or "not met" for each patient. The total of "met" and "not met" criteria will be aggregated across patients. The percentage of goal-directed sepsis criteria met will be calculated as "met" criteria divided by the sum of "met" plus "not met" criteria.

次要结局

  • Length of hospital stay(Time of ED presentation to the time of in-hospital death or hospital discharge, approximately 2 weeks)
  • In-hospital mortality(Time of ED presentation to the time of in-hospital death or hospital discharge, approximately 2 weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Harman S. Gill

Principal Investigator, Assistant Professor of Emergency Medicine and Medicine

Dartmouth-Hitchcock Medical Center

研究点 (2)

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