Prospective cohort study: evaluation of the treatment of deep thermal Hand burns in Adults with NexoBrid® in the Dutch populatio
Recruiting
- Conditions
- burn scars10014982
- Registration Number
- NL-OMON46955
- Lead Sponsor
- Rode Kruis Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 10
Inclusion Criteria
* *18 years
* Patients with clinically judged acute deep partial thickness or mixed deep partial and full thickness burns of one or both hands that are treated with NexoBrid®
* Competent or temporary incompetent (because of sedation and/or intubation)
Exclusion Criteria
* Insufficient knowledge of the Dutch language
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Hand function as measured by the modified Kapandji Index (MKI), goniometry,<br /><br>sensation, strength, Jebsen-Taylor test </p><br>
- Secondary Outcome Measures
Name Time Method <p>Scar quality as measured by the POSAS and quality of life as measured by<br /><br>validated questionnaires.<br /><br>Other secondary study parameters include: the incidence of patients requiring<br /><br>surgical excision and percentage of surgical excision, the incidence of<br /><br>patients requiring autografting and percentage of autografting, the time to<br /><br>reach wound healing (defined as re-epithelialization >95%), the need for<br /><br>escharotomy due to burn-induced compartment syndrome, the incidence of<br /><br>bacterial colonization and wound infection, the length of hospital stay, pain,<br /><br>itching, edema, return to work and the description of the revalidation<br /><br>treatment.<br /><br><br /><br>Other study parameters include: age, gender, Body Mass Index (BMI), cause of<br /><br>burn, TBSA%, BSA% of the hands, co-morbidities, medication.</p><br>