Effects of a Community-Based Tai Chi Chuan and Aerobic Exercise Program on Cognitive Function, Physical Function and Quality of Life in Older Adults with Mild Cognitive Impairment: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- Not Applicable
- 发起方
- 入组人数
- 180
- 试验地点
- 1
- 主要终点
- Cognitive Function by Montreal Cognitive Assessment (MOCA), Mini-Mental State Examination (MMSE)
研究概览
简要总结
This randomized controlled trial will assess the effects of a 12 weeks community-based Tai Chi Chuan and aerobic exercise program on cognitive, physical, and quality of life outcomes in 180 older adults (60 years or above) with mild cognitive impairment in Bangladesh. Eligible participants will be randomly assigned to Tai Chi Chuan, aerobic exercise, or wait list control groups, training three times per week under supervision. Individuals with severe sensory, medical, or neurological conditions will be excluded. Outcomes (MoCA, MMSE, SPPB, TUG, SF 36) will be measured at baseline, 12, and 24 weeks to evaluate intervention effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 60.00 Year(s) 至 85.00 Year(s)（—）
- 性别
- All
入选标准
- •Participants will be included if they have mild cognitive impairment without dementia, are aged 60 years old or above, can perform the designated exercise program, have not engaged in regular exercise in the past 3 months, and have provided informed consent and volunteered for participation.
排除标准
- •Participants will be excluded if they have severe visual or auditory impairment, serious medical conditions in major organs (such as heart, lung, kidney, liver and so on), other neurological disorders, or a history of alcohol or drug abuse.
结局指标
主要结局
Cognitive Function by Montreal Cognitive Assessment (MOCA), Mini-Mental State Examination (MMSE)
时间窗: At baseline, 12 weeks, and 24 weeks
次要结局
- Physical Function by Short Physical Performance Battery (SPPB) and Timed Up and Go Test (TUG); Quality of Life by Short Form Survey (SF-36)(At baseline, 12 weeks, and 24 weeks)
研究者
Kazi Md Azman Hossain
Jashore University of Science and Technology (JUST), Jashore