An evaluation of improving dialysis adequacy in large haemodialysis patients: the double dialyser study

Not Applicable

Completed

• Conditions: Kidney failure/haemodialysis; Urological and Genital Diseases; Renal failure

• Registration Number: ISRCTN92573528
• Lead Sponsor: Kidney Foundation of Canada (Canada)

Brief Summary

2009 Results article in https://pubmed.ncbi.nlm.nih.gov/19619920/ (added 05/08/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2004-07-01
• Study Start: 2007-09-27
• Last Update Posted: 17 August 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

1. Patients on a stable regimen of haemodialysis greater than or equal to 3 months
2. Dry weight greater than or equal to 80 kg
3. Kt/V less than 1.2 on two occasions in the previous 6 months or requirement for greater than 12 hours of haemodialysis per week because of a history of inadequate dialysis
4. Blood flow rate greater than 350 ml/min through a well functioning access
5. Aged greater than 18, both sexes

Exclusion Criteria

1. Scheduled renal transplant in the next 6 months
2. Contraindication to intradialytic anticoagulation
3. Requirement for greater than 4.5 hours of haemodialysis three times per week for the purpose of volume removal due to excessive interdialytic weight gains or intradialytic hypotension/cramping
4. Failure to provide informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified