Incidence of Post Induction Hypotension with varying doses of propofol- A Randomized conrol trial.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 168
- 试验地点
- 1
- 主要终点
- To evaluate the hemodynamic changes post induction with different doses of propofol by studying the vital signs in 2 groups for 10 minutes post induction.
研究概览
简要总结
A rondomized control study to assess the incidence of post indution hypotension in patient underfoing general anyesthesia needing an endotracheal tube placement with 2 doses of propofol. The HR, SBP, DBP, MAP will be assessed from 3 minutes before induction to 10 minutes after intubation, along with the airway assessment and scopy duration. The need for pressor treatment will be documented.
The intubation quality score, Ramsay sedation score and aldrete score will be assess at intubation, extubation and discharge from PACU respectively.
Sample size of 84 in each group- Total of 168.
The duration of study is 6 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA I/II patients
- •Patients between the ages of 18 years and 49 years of any gender.
- •Patiets undergoing genral ananesthesia with endotracheal tube placement.
排除标准
- •Patient refusal to participate in the study
- •Patient allergic to propofol
- •ASA III/IV grading of patients
- •Patients undergoing surgeries which do not need general anaesthesia or placement of endotracheal tube.
结局指标
主要结局
To evaluate the hemodynamic changes post induction with different doses of propofol by studying the vital signs in 2 groups for 10 minutes post induction.
时间窗: To evaluate the hemodynamic changes post induction with different doses of propofol by studying the vital signs 2 groups for 10 minutes post induction.
次要结局
- 1. To asses the Induction quality score for 2 doses of propofol(2. To assess Ramsay sedation score at extubation.)
研究者
Dr H S MURTHY
Manipal Hospitals, OLd airport road Bangalore.