Assessing fluid responsiveness, peripheral perfusion and arterial load for hypotension prediction during fluid withdrawal in critically ill patients

• Conditions: Critical ill Patient with fluid overload are associated morbidity and mortality. However ,fluid removal need to be done without complication.; Hemodynamic; De-escalation; Diuretic; Acute kidney injury

• Registration Number: TCTR20230426001
• Lead Sponsor: Dr. Korn chotchaisthit

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-04-26
• Study Completion: 2024-03-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

1.Patient age 18-75 yrs.
2.Admit in ICU with cardiac output monitoring
3.Vital sign Stable and No need for further resuscitation or minimal dose of vasoactive agent (Dose < 0.05 microgram/kg/hr.)
4.Patient with evidence of accumulated fluid in the body and attention physician design to give diuretic drug to excrete fluid

Exclusion Criteria

1.Patient can not test fluid responsiveness by passive leg raising test
2.ESRD patient with hemodialysis
3. Patient post kidney transplantation
4.Patients who refuse to participate in the study or request to withdraw from the study

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sensitivity and specificity of passive leg raising test in hypotension prediction after fluid removal 6 and 24 hours Blood pressure and Serum creatinine

Secondary Outcome Measures

Name	Time	Method
Sensitivity and specificity of passive leg raising test, peripheral perfusion, arterial load in hypotension prediction after fluid removal 6 and 24 hours Blood pressure and Serum creatinine