The Effect of Restrictive Fluid and Vasopressin During Surgery of Burn Patients: a Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 入组人数
- 158
- 试验地点
- 1
- 主要终点
- Intraoperative blood loss
研究概览
简要总结
This is a randomized double-blinded study to investigate in which the groups are designated as the control group and the restrictive group to further evaluate significant differences in intraoperative blood loos during burn surgery.
详细描述
This is a randomized double-blinded study to investigate the effect of fluid restriction and vasopressin on blood loss during surgery of the burn patients. The groups are designated as the control group and the restrictive group to further evaluate significant differences in intraoperative blood loss during the surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Restrictive group
Intervention: administration of vasopressin 0.01 - 0.04 U/min after induction of anesthesia.
Intraoperative fluid management: administration of 2-4 ml/kg/hr of crystalloid solution.
干预措施: Vasopressin (Drug)
结局指标
主要结局
Intraoperative blood loss
时间窗: At the end of the surgery, approximately 3 hrs
Comparison of the amounts of estimated blood loss in the two groups.
次要结局
- Intraoperative red blood cell transfusion(At the end of the surgery, approximately 3 hrs)
- Postoperative pulmonary complication(Within 7 postoperative days)
- Postoperative cardiovascular complication(Within 7 postoperative days)
- Postoperative renal complication(Within 7 postoperative days)
研究者
Hee Yeong Kim
Assistant Professor
Hangang Sacred Heart Hospital